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Updated: Sep 30, 2025

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
Published on: February 7, 2018
Artificial intelligence approaches to the biochemistry of oxidative stress: Current state of the art
Igor Pantic1, Jovana Paunovic2, Snezana Pejic3
1University of Belgrade, Faculty of Medicine, Institute of Medical Physiology, Laboratory for Cellular Physiology, Visegradska 26/II, RS-11129, Belgrade, Serbia; University of Haifa, 199 Abba Hushi Blvd, Mount Carmel, Haifa, IL, 3498838, Israel; Ben-Gurion University of the Negev, Faculty of Health Sciences, Department of Physiology and Cell Biology, 84105 Be'er Sheva, Israel.
Abstract:
Artificial intelligence (AI) and machine learning models are today frequently used for classification and prediction of various biochemical processes and phenomena. In recent years, numerous research efforts have been focused on developing such models for assessment, categorization, and prediction of oxidative stress. Supervised machine learning can successfully automate the process of evaluation and quantification of oxidative damage in biological samples, as well as extract useful data from the abundance of experimental results. In this concise review, we cover the possible applications of neural networks, decision trees and regression analysis as three common strategies in machine learning. We also review recent works on the various weaknesses and limitations of artificial intelligence in biochemistry and related scientific areas. Finally, we discuss future innovative approaches on the ways how AI can contribute to the automation of oxidative stress measurement and diagnosis of diseases associated with oxidative damage.
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