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Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice
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Auditory brainstem responses obtained with randomised stimulation level.

Marta Martinez1,2,3, Joaquin T Valderrama4,5, Isaac M Alvarez6,7

  • 1ENT Service, San Cecilio University Hospital, Granada, Spain.

International Journal of Audiology
|March 17, 2022
PubMed
Summary
This summary is machine-generated.

Randomised stimulation level (RSL) offers a faster auditory brainstem response (ABR) assessment with similar signal morphology. The general population also found RSL stimuli more comfortable, suggesting improved clinical potential.

Keywords:
Response trackinghearing comfortresponse detectiontest time

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Area of Science:

  • Audiology
  • Neuroscience
  • Biomedical Engineering

Background:

  • Auditory brainstem response (ABR) testing traditionally uses sequential stimulation levels.
  • A novel stimulation paradigm, randomised stimulation level (RSL), has been developed.

Purpose of the Study:

  • To introduce and evaluate the randomised stimulation level (RSL) paradigm for ABR testing.
  • To compare RSL with the conventional sequential stimulation paradigm.
  • To assess the audiological comfort of RSL.

Main Methods:

  • Auditory brainstem responses (ABRs) were recorded from 11 normal-hearing adults using both conventional and RSL paradigms.
  • Morphology of elicited ABR signals was compared between the two paradigms.
  • An online survey of 238 adults assessed the perceived comfort of RSL stimuli.

Main Results:

  • Both RSL and conventional paradigms produced ABR signals of comparable morphology.
  • RSL enabled a more rapid and comprehensive overview of the ABR session.
  • The general community reported greater comfort with RSL stimuli compared to conventional stimuli.

Conclusions:

  • RSL is a viable alternative to conventional ABR stimulation, offering similar signal quality.
  • The RSL paradigm enhances efficiency and patient comfort in ABR testing.
  • RSL facilitates early application of response tracking strategies, potentially improving diagnosis of abnormal ABRs.