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Related Experiment Video

Updated: Sep 30, 2025

Fabricating Highly Open Porous Microspheres HOPMs via Microfluidic Technology
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Manufacturing polymeric porous capsules.

Claudia Contini1,2, Wenyi Hu1, Yuval Elani1,2

  • 1Department of Chemical Engineering, Imperial College London, Exhibition Road, London SW7 2AZ, UK. c.contini@imperial.ac.uk.

Chemical Communications (Cambridge, England)
|March 17, 2022
PubMed
Summary

Polymeric porous capsules enable size-selective material exchange, crucial for drug delivery and synthetic biology. Their controlled pore size allows small molecule passage while retaining larger ones.

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Area of Science:

  • Materials Science
  • Chemical Engineering
  • Biotechnology

Background:

  • Polymeric porous capsules offer size-selective material exchange.
  • Their porous core-shell structure enhances permeability for small molecules.
  • Applications include drug delivery, microreactors, and synthetic biology.

Purpose of the Study:

  • To review manufacturing strategies for polymeric porous capsules.
  • To provide guidance on designing capsules with controlled pore size.

Main Methods:

  • Review of existing literature on capsule fabrication.
  • Analysis of factors influencing pore size and permeability.

Main Results:

  • Various fabrication methods exist for creating polymeric porous capsules.

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  • Pore size is tunable based on molecular composition and fabrication technique.
  • Controlled pore size is key to selective material exchange.

    • Conclusions:

    • Polymeric porous capsules are versatile systems for controlled material transport.
    • Understanding fabrication and composition is vital for designing capsules with specific pore sizes.
    • These capsules hold significant potential across diverse scientific fields.