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Updated: Aug 9, 2026

Programmed Electrical Stimulation in Mice
Published on: May 26, 2010
Distal atrioventricular conduction system function
Insights
Electrophysiologic studies are rarely needed for chronic bifascicular block, as complete heart block progression is uncommon. Current use focuses on specific cases of heart block or unexplained fainting.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Background:
- Chronic bifascicular block was historically associated with high risk of complete atrioventricular (AV) block and sudden death.
- Electrophysiologic studies, including H-V interval measurement, were proposed to identify high-risk patients for prophylactic treatment.
Purpose of the Study:
- To evaluate the current role of electrophysiologic studies in managing patients with chronic bifascicular block.
- To reassess the risk of progression to complete AV block and its impact on mortality.
Main Methods:
- Review of clinical investigations and electrophysiologic data in patients with chronic bifascicular block.
- Analysis of outcomes, including progression to complete AV block and cardiovascular mortality.
Main Results:
- Progression to complete AV block in chronic bifascicular block is rare.
- Cardiovascular mortality, including sudden death, is significant but primarily linked to underlying organic heart disease, not AV block progression.
- Electrophysiologic studies are useful for locating the site of documented AV block and evaluating unexplained syncope.
Conclusions:
- The feared progression to complete AV block is uncommon in chronic bifascicular block.
- Mortality in these patients is mainly due to underlying heart disease.
- Electrophysiologic evaluation is reserved for specific indications like documented AV block or unexplained syncope.
Abstract:
This article addresses electrophysiologic evaluation of the distal AV conduction system in patients with chronic bifascicular block. It was formerly thought that progression to complete AV block was a common cause of morbidity and even sudden death in this condition, and it was hoped that electrophysiologic evaluation, including measurement of the H-V interval, would facilitate prospective identification and prophylactic treatment of patients prone to these complications. However, a decade of clinical investigation has revealed that progression to complete AV block is rare and that although cardiovascular mortality, including sudden death, is substantial, this mortality usually relates to underlying organic heart disease. The current role for electrophysiologic studies in chronic bifascicular block is limited to delineation of the site of electrocardiographically documented second- or third-degree AV block and to the evaluation of unexplained syncope.
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