Related Experiment Video
Updated: Sep 29, 2025
Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
Preparation and characterization of Sargassum pallidum polysaccharide nanoparticles with enhanced antioxidant
Ke Zhang1, Chun Chen1, Qiang Huang2
1SCUT-Zhuhai Institute of Modern Industrial Innovation, School of Food Science and Engineering, South China University of Technology, 381 Wushan Road, Guangzhou, China.
Abstract:
Sargassum pallidum polysaccharide nanoparticle (nSPP-30) was prepared via antisolvent precipitation method and the preparation conditions were optimized. The effects of nanocrystallization on the structure and biological activities of S. pallidum polysaccharide were investigated. Under the optimal preparation condition, the average particle size, polydispersity index (PDI), and ξ-potential of nSPP-30 were 229.63 nm, 0.407, and -28.43 mV, respectively. Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD) analyses indicated that nanocrystallization did not change primary and crystal structures of S. pallidum polysaccharide. However, nanocrystallization could improve the swelling, thermodynamic, and antioxidant properties of S. pallidum polysaccharide. In addition, the thymol adsorption capacity of nSPP-30 was enhanced as compared to the corresponding polysaccharide. These results suggest that nSPP-30 can be developed as a potential antioxidant or natural nano-carrier to encapsulate thymol for practical applications.
