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Updated: Sep 29, 2025
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Evaluation of macular vessel density changes after strabismus surgery using optical coherence tomography angiography
Aldo Vagge1, Paolo Nucci2, Lorenzo Ferro Desideri1
1IRCCS Ospedale Policlinico San Martino, Genova, Italy; Università di Genova, DiNOGM, Italy I.
Purpose:
To compare retinal vessel density before and after strabismus surgery using swept-source optical coherence tomography angiography (SS-OCTA).
Methods:
In this longitudinal, single-arm pilot study, vascular density in the deep capillary plexus (DCP), superficial retinal capillary plexus (SCP) and choriocapillaris layer (CCL) in consecutive subjects undergoing strabismus surgery was assessed using SS-OCTA preoperatively (T0), on the first day postoperatively (POD1), and 30 days postoperatively (POD30).
Results:
A total of 92 eyes of 56 patients (54% males) were included. Mean patient age was 41.1 ± 22.7. OCT vascular density of the DCP was 50.20 ± 5.57 at T0, 52.74 ± 4.77 at POD1, and 50.92 ± 4.58 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). Vascular density of the CCL was 50.72 ± 4.80 at T0, 53.59 ± 3.65 at POD1, and 51.39 ± 4.64 at POD30. The differences were statistically significant for T0 versus POD1 (P < 0.05). No significant differences were found in SCP (P > 0.05).
Conclusions:
Transitory hemodynamic changes can occur in the DCP and in the CCL following muscle recession procedures.
