Related Experiment Video
Updated: Sep 29, 2025

09:32
Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion
Published on: April 11, 2018
9.8K
Obtaining anatomic motion and laxity characteristics in a total knee design
Peter S Walker1, Ilya Borukhov1, Sally LiArno1
1NYU Langone Orthopedic Hospital, New York, NY, United States.
The Knee
|March 21, 2022
Summary
Guided Motion total knee designs more closely replicate natural knee movement compared to standard designs. Further research using simulators or computer models is recommended to explore potential improvements in patient outcomes.
Area of Science:
- Biomechanical Engineering
- Orthopedic Surgery
- Medical Device Design
Background:
- Reproducing normal knee motion is a primary objective in total knee replacement (TKR) design.
- Current TKR designs often fail to achieve the goal of replicating natural knee kinematics.
- Guided Motion (GM) TKR designs were developed to offer more anatomic motion than standard prostheses.
Purpose of the Study:
- To evaluate the kinematic performance of novel Guided Motion total knee designs.
- To compare the motion patterns of GM knees with a standard posterior-stabilized (PS) knee and anatomic knee motion.
Main Methods:
- GM knee designs were created using a computer-aided method, generating bearing surfaces based on desired motion.
- A specialized knee testing machine applied physiological forces (compression, shear, torque) during flexion.
- Neutral path of motion and laxity were measured, adapting ASTM standard Constraint Test protocols.
Main Results:
- Kinematic analysis revealed that GM knees exhibited motion patterns closer to anatomic knee motion.
- Comparison with a standard PS knee demonstrated superior kinematic replication by the GM designs.
- Results were benchmarked against previously determined anatomic motion data from knee specimens.
Conclusions:
- The study provides evidence supporting the potential of GM designs to achieve more anatomic knee motion.
- Further in vitro evaluations using knee simulators or advanced computer modeling are warranted.
- Successful in vivo reproduction of anatomic motion could lead to enhanced clinical outcomes for TKR patients.
Related Concept Videos
Development of the Limb Synovial Joints
1.7K
Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...
1.7K
Knee Joint
2.4K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
2.4K
Eccentric Axial Loading in a Plane of Symmetry
315
Eccentric axial loading occurs when an axial load is applied away from the centroidal axis of a structural member. This scenario is common in engineering, where structural elements may not be directly aligned due to various design or functional requirements.
315
Anatomical Movements
12.5K
Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist,...
12.5K

