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Prkg2 regulates alveolar type 2-mediated re-alveolarization

Mo Zhang1,2, Gibran Ali1, Satoshi Komatsu1

  • 1Department of Cellular and Molecular Biology, University of Texas at Tyler, 11937 US Highway 271, Tyler, TX, 75708-3154, USA.

Stem Cell Research & Therapy
|March 22, 2022
PubMed
Summary

The cGMP-dependent type 2 protein kinase (PRKG2) influences alveolar type 2 cell fate. PRKG2 deficiency alters cell differentiation and proliferation, impacting lung repair, especially with endotoxin exposure.

Keywords:
DifferentiationLung injuryOrganoidsPrkg2Proliferation

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