Related Experiment Video
Updated: Sep 29, 2025

Methods to Test Endocrine Disruption in Drosophila melanogaster
Published on: July 3, 2019
COVID-19 and the Endocrine System: A Review of the Current Information and Misinformation
Samir Ahmed Mirza1, Abdul Ahad Ehsan Sheikh2, Michaela Barbera3
1Department of Internal Medicine, Dow Medical College, Karachi 74200, Pakistan.
Abstract:
Coronavirus disease 2019 (COVID-19) infection primarily involves the respiratory system but has many noteworthy extra pulmonary manifestations as well. We write this review to highlight the basis of some pathophysiological mechanisms of COVID-19 infection-induced endocrine dysfunction. Different scientific databases and institutional websites were searched to collect and consolidate the most up-to-date data relating to COVID-19 infection and endocrine systems. Hypopituitarism, central diabetes insipidus, SIADH, thyroid abnormalities, hyperglycemia, adrenal insufficiency, orchitis and alteration in sperm morphology have been reported in case reports of patients with COVID-19 infection. Data focusing on COVID-19 vaccination was also searched to summarize the effect, if any, on the endocrine system. Endocrinopathies noted post COVID-19 vaccination, including cases of adrenal hemorrhage, new onset Type II Diabetes Mellitus and subacute thyroiditis, are also discussed in this review. This review calls attention to the misinformation relating to COVID-19 vaccination with supposed endocrine effects such as infertility and problems with pregnancy. Rebutting these misconceptions can help increase compliance and maximize COVID-19 vaccination to the public.
Related Concept Videos
An Overview of the Endocrine System
The endocrine system collaborates...
What is the Endocrine System?
Structures of the Endocrine System
The Endocrine System
Regulation of Hormone Secretion
Humoral...
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...

