Successive Diels-Alder Cycloadditions of Cyclopentadiene to [10]CPP⊃C₆₀: A Computational Study

Fullerenes have potential applications in many fields. To reach their full potential, fullerenes have to be functionalized. One of the most common reactions used to functionalize fullerenes is the Diels-Alder cycloaddition. In this case, it is important to control the regioselectivity of the cycloaddition during the formation of higher adducts. In C₆₀, successive Diels-Alder cycloadditions lead to the T_h-symmetric hexakisadduct. In this work, we explore computationally using density functional theory (DFT) how the presence of a [10]cycloparaphenylene ring encapsulating C₆₀ ([10]CPP⊃C₆₀) affects the regioselectivity of multiple additions to C₆₀. Our results show that the presence of the [10]CPP ring changes the preferred sites of cycloaddition compared to free C₆₀ and leads to the formation of the tetrakisadduct. Somewhat surprisingly, our calculations predict formation of this particular tetrakisadduct to be more favored in [10]CPP⊃C₆₀ than in free C₆₀.