Related Experiment Video
Updated: Sep 29, 2025

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
[Isocyanate-induced asthma]
Jesper Bælum1, Iben Brock Jacobsen1, David Sherson1
1Arbejds- og Miljømedicinsk Klinik, Odense Universitetshospital.
Abstract:
Isocyanates are often found in workplaces in e.g., glue, paint, plastics and foam products. Asthma caused by isocyanates is one of the most common forms of occupational asthma, though it is difficult to diagnose, as described in this review. It is not possible to demonstrate sensitisation with available allergy tests. A certain diagnosis can only be made with the help of specific bronchial provocation, which is performed at three centres in Denmark. A correct diagnosis is important, as it helps provide optimal treatment as well as alerting the employer, that improvements are needed at the workplace.
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