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Related Experiment Video

Updated: Sep 29, 2025

Translational Rabbit Model of Chronic Cardiac Pacing
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Towards a Leadless Wirelessly Controlled Intravenous Cardiac Pacemaker.

Usama Anwar, Olujimi A Ajijola, Kalyanam Shivkumar

    IEEE Transactions on Bio-Medical Engineering
    |March 23, 2022
    PubMed
    Summary

    This study introduces a leadless, batteryless cardiac pacemaker powered wirelessly, potentially solving lead and battery issues in current devices. This innovation offers a new solution for cardiac pacing.

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    Area of Science:

    • Biomedical Engineering
    • Medical Devices
    • Cardiovascular Technology

    Background:

    • Traditional pacemakers face lead complications like fracture and dislodgement.
    • Leadless pacemakers have limited battery life, requiring replacement.
    • Existing solutions do not fully address lead and battery issues in cardiac pacing.

    Purpose of the Study:

    • To present a novel leadless and batteryless, wirelessly powered intravenous cardiac pacemaker.
    • To mitigate lead-related complications and battery replacement needs in cardiac pacing devices.

    Main Methods:

    • Wireless power transfer at 13.56 MHz in bursts for pacing.
    • CMOS technology for miniaturization of the stimulation module.
    • Design for anatomical fit within cardiac veins, low power consumption, and high stimulation voltage.

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    Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
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    Last Updated: Sep 29, 2025

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    Main Results:

    • Demonstrated ex-vivo pacing with 5 V stimulation and 1 mW power consumption.
    • Achieved wireless pacing up to 2.5 cm transmitter-receiver separation.
    • Verified in-vivo functionality by increasing heart rate in a Yorkshire pig from 64 to 100 bpm.

    Conclusions:

    • Intravascular cardiac pacing is achievable, mitigating lead and battery complications.
    • This technology advances leadless and wirelessly powered pacemaker solutions.