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Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
Role of surgery in multifocal glioblastoma
Syeda Kubra Kishwar Jafri1, Syed Sarmad Bukhari2, Muhammad Shahzad Shamim3
1Section of Neurosurgery, Aga Khan University Hospital, Karachi.
Abstract:
The management of multifocal glioblastomas is a point of constant discussion amongst neuro-oncologists. Best outcomes in glioblastoma management come from gross total resection (GTR) followed by concomitant radiation and chemotherapy (CCRT). Multifocal disease is resistant to GTR. Conventional management of these lesion is usually biopsy only followed by CCRT. Recent evidence has shown that there may be some benefit to attempting GTR of the largest lesion whenever safe to do so.
