Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

720
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
720
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

849
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
849
Glaucoma: Overview01:25

Glaucoma: Overview

927
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
927
Subviral Agents01:29

Subviral Agents

154
Subviral agents are infectious entities that resemble viruses but lack one or more viral components, such as a capsid or essential replication machinery. These agents include viroids, prions, and satellites, each possessing distinct structural and functional characteristics that influence their mode of infection and replication.Viroids are the simplest subviral agents, consisting of circular, single-stranded RNA molecules without a protein coat. They exclusively infect plants, relying entirely...
154
Acute Pharyngitis01:30

Acute Pharyngitis

1.8K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.8K
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

996
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
996

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune Checkpoint Inhibitor-Associated Uveitis Treated with the 0.19 Mg Fluocinolone Acetonide Intravitreal Implant: Clinical Outcomes in a Retrospective Case-Series.

Ocular immunology and inflammation·2026
Same author

TRP-Dependent Calcium Regulation in HCEC-12 Cells: Involvement of Ascorbic Acid and Cannabinoid Receptor Signaling.

International journal of molecular sciences·2026
Same author

QuantiFERON-TB gold test: a valuable diagnostic tool for tubercular uveitis in non-endemic regions.

Infection·2026
Same author

Navigating the Therapeutic Landscape of Non-Infectious Uveitis Despite Major Gaps.

Biomedicines·2025
Same author

[Noninfectious conjunctivitis].

Klinische Monatsblatter fur Augenheilkunde·2025
Same author

Ocular Mucosal Pemphigoid: Diagnosis, Clinic and Therapy.

Klinische Monatsblatter fur Augenheilkunde·2025
Same journal

Surgical Management of Malignant Eyelid Tumors: A Retrospective Analysis over 10 Years of Surgical Treatment in 1443 Consecutive Cases.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

[Ocular Penetration - Management of Ophthalmic Trauma].

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Corneal Neurotisation in Neurotrophic Keratopathy: A Retrospective Analysis of Functional Outcomes and Clinical Courses.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Evaluating the Long-term Success and Safety of Canaloplasty in Glaucoma Patients.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Imbalanced Trace Elements as Risk Factors in the Pathogenesis of Glaucoma.

Klinische Monatsblatter fur Augenheilkunde·2026
Same journal

Malnutrition as a Risk Factor for Cerebral and Glaucomatous Neurodegeneration - Mechanisms and Therapeutic Strategies.

Klinische Monatsblatter fur Augenheilkunde·2026
See all related articles

Related Experiment Video

Updated: Sep 29, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.8K

Viral Anterior Uveitis.

Karoline Baquet-Walscheid1,2, Dominika Pohlmann3,4, Uwe Pleyer3

  • 1Augenzentrum am St. Franziskus-Hospital, Münster, Deutschland.

Klinische Monatsblatter Fur Augenheilkunde
|March 23, 2022
PubMed
Summary
This summary is machine-generated.

Diagnosing viral anterior uveitis (AU) relies on clinical signs, but PCR and antibody tests aid difficult cases. Viral AU management varies, with potential risks of secondary glaucoma requiring intervention.

More Related Videos

Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease
10:14

Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease

Published on: April 19, 2015

15.2K
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.2K

Related Experiment Videos

Last Updated: Sep 29, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

2.8K
Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease
10:14

Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease

Published on: April 19, 2015

15.2K
Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

5.2K

Area of Science:

  • Ophthalmology
  • Virology
  • Immunology

Background:

  • Viral anterior uveitis (AU) diagnosis can be challenging despite typical clinical signs like anterior chamber inflammation.
  • Keratic precipitate morphology and intraocular pressure (IOP) fluctuations during relapse are key diagnostic indicators.
  • Advanced diagnostic methods like PCR and antibody testing (Goldmann-Witmer coefficient) offer high specificity but limited sensitivity.

Purpose of the Study:

  • To outline the diagnostic approaches for viral anterior uveitis (AU).
  • To discuss the management strategies for different viral causes of AU.
  • To highlight the long-term complications associated with recurrent viral AU.

Main Methods:

  • Clinical assessment of anterior chamber inflammation, keratic precipitates, and IOP.
  • Analysis of aqueous humor using Polymerase Chain Reaction (PCR) and antibody testing (Goldmann-Witmer coefficient).
  • Review of treatment protocols for specific viral etiologies including Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), Cytomegalovirus (CMV), and Rubella.

Main Results:

  • Clinical diagnosis is often sufficient, but laboratory tests are valuable in complex cases.
  • Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), and Cytomegalovirus (CMV) uveitis necessitate antiviral and anti-inflammatory treatments, potentially including antiglaucomatous therapy.
  • Rubella-associated AU lacks specific antiviral treatment, requiring cautious steroid use due to adverse effects.

Conclusions:

  • Effective management of viral AU requires accurate diagnosis and tailored treatment strategies.
  • Recurrent viral AU poses a significant risk for secondary glaucoma, often necessitating surgical intervention.
  • Ophthalmologists must consider the specific viral agent and potential complications for optimal patient outcomes.