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Dechorionation of Medaka Embryos and Cell Transplantation for the Generation of Chimeras
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Chromatophoromas in Reptiles.
Colleen F Monahan1, Michael M Garner2, Matti Kiupel3
1New Hampshire Veterinary Diagnostic Laboratory, University of New Hampshire, Durham, NH 03824, USA.
Veterinary Sciences
|March 24, 2022
Summary
Chromatophoromas are pigment cell tumors in reptiles, amphibians, and fish. Diagnosis involves histology, and surgical excision is the primary treatment for these neoplasms.
Area of Science:
- Comparative Oncology
- Herpetology
- Dermatopathology
Background:
- Chromatophoromas are neoplasms originating from pigment cells (chromatophores) in ectothermic vertebrates.
- These tumors encompass melanophoromas (melanomas), iridophoromas, and xanthophoromas.
- While often spontaneous, oncogenesis may involve genetic and environmental factors.
Purpose of the Study:
- To review the clinical presentation, gross appearance, and diagnostic methods for chromatophoromas in reptiles.
- To describe the clinical behavior and current treatment strategies for reptilian chromatophoromas.
Main Methods:
- Histologic examination is the primary diagnostic tool.
- Immunohistochemistry and electron microscopy aid in diagnosing poorly differentiated or pigmented neoplasms.
- Review of existing literature on chromatophoroma presentation, diagnosis, and treatment in reptiles.
Main Results:
- Chromatophoromas present with varied gross appearances depending on cell type.
- Histopathology confirms diagnosis, with advanced techniques assisting challenging cases.
- Aggressive surgical excision is the recommended treatment modality.
Conclusions:
- Accurate diagnosis of chromatophoromas relies on integrated histopathological and ancillary techniques.
- Surgical intervention offers the best prognosis for reptilian chromatophoromas.
- Further research into oncogenesis and novel treatments is warranted.
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