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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Unique presentations of aspergillosis endogenous endophthalmitis in two hospitalized patients with severe COVID-19
Alaa E Fayed1, Ismail I Hamza2, Sherif N Embabi3
1Department of Ophthalmology, Kasr Al-Ainy School of Medicine, Cairo University, Giza; Watany Eye Hospital, Cairo, Egypt.
Abstract:
We present two ICU-hospitalized patients with coronavirus disease-19 (COVID-19) presenting with endogenous endophthalmitis in one eye and variable manifestations of chorioretinitis in the fellow eye. Two diabetic patients (57 and 62 years old) showed anterior uveitis and yellowish-white subretinal infiltrations. The fellow eye of one patient showed patches of choroiditis, while the other showed full retinal thickness infiltrations. A workup yielded high serum titers of galactomannan, diagnostic of aspergillosis. The widespread use of high doses of corticosteroids in the management of COVID-19 may predispose to various secondary fungal opportunistic infections and may manifest in different forms of chorioretinal infiltration.
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