Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ibuprofen therapy for dysmenorrhea.

S L Corson, R J Bolognese

    The Journal of Reproductive Medicine
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hysterectomy, endometrial ablation and Mirena® for heavy menstrual bleeding: a systematic review of clinical effectiveness and cost-effectiveness analysis.

    Health technology assessment (Winchester, England)·2011
    Same author

    Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients.

    BMJ (Clinical research ed.)·2010
    Same author

    Evaluation of the subfertile couple: the fine points.

    International journal of fertility and women's medicine·2002
    Same author

    Survey of laparoscopic entry injuries provoking litigation.

    The Journal of the American Association of Gynecologic Laparoscopists·2001
    Same author

    A multicenter evaluation of endometrial ablation by Hydro ThermAblator and rollerball for treatment of menorrhagia.

    The Journal of the American Association of Gynecologic Laparoscopists·2001
    Same author

    Female reproductive endocrinology at the turn of the millennium.

    International journal of fertility and women's medicine·2001

    Ibuprofen was found to be statistically superior to aspirin and placebo for relieving menstrual pain in a study of 33 women. Patients also preferred ibuprofen, highlighting its effectiveness in managing dysmenorrhea.

    Area of Science:

    • Pharmacology
    • Gynecology
    • Pain Management

    Background:

    • Dysmenorrhea, or painful menstruation, significantly impacts women's quality of life.
    • Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for pain relief.
    • Comparative efficacy of different NSAIDs for dysmenorrhea requires further investigation.

    Purpose of the Study:

    • To compare the efficacy of ibuprofen, aspirin, and placebo in treating dysmenorrhea.
    • To assess patient preference for pain relief medication during dysmenorrhea.

    Main Methods:

    • A double-blind, placebo-controlled, crossover study design was employed.
    • Thirty-three patients with dysmenorrhea participated in the study.
    • Each patient received ibuprofen, aspirin, and placebo during three successive menstrual cycles in a randomized sequence.
    Keywords:
    Age FactorsAmericasComparative StudiesContraceptive UsageDeveloped CountriesDiseasesDysmenorrheaEvaluationMenstruation DisordersNorth AmericaNorthern AmericaPainParityPennsylvaniaPopulation CharacteristicsResearch MethodologySigns And SymptomsStudiesTreatmentUnited States

    Related Experiment Videos

    Main Results:

    • Ibuprofen demonstrated statistically significant superiority over both aspirin and placebo in relieving dysmenorrhea pain.
    • Patient drug preference data corroborated the objective findings, with a higher preference for ibuprofen.
    • The study confirmed ibuprofen's effectiveness in managing pain associated with dysmenorrhea.

    Conclusions:

    • Ibuprofen is a highly effective treatment for dysmenorrhea pain.
    • NSAIDs, particularly ibuprofen, play a crucial role in the therapeutic management of painful menstruation.
    • Further research can explore optimal dosing and long-term effects of NSAIDs for dysmenorrhea.