Biodegradable Mg-Zn-Ca-Based Metallic Glasses

Area of Science:

• Biomaterials Science
• Materials Engineering
• Biomedical Engineering

Background:

• Biodegradable Mg-Zn-Ca-based metallic glasses (MGs) exhibit superior strength and corrosion resistance over crystalline Mg.
• These MGs demonstrate excellent biocompatibility in vivo and in vitro, making them promising for temporary implants.

Purpose of the Study:

• To review the microstructure and mechanical properties of Mg-Zn-Ca-based MGs.
• To provide a comprehensive understanding of the biocorrosion and biocompatibility of these MGs.
• To propose future directions for fabrication, composition, structure, and reinforcement.

Main Methods:

• Literature review of Mg-Zn-Ca-based metallic glasses.
• Analysis of microstructure and mechanical property data.
• Synthesis of information on biocorrosion and biocompatibility studies.

Main Results:

• Mg-Zn-Ca MGs show enhanced mechanical properties and corrosion resistance compared to crystalline Mg.
• Excellent biocompatibility is confirmed, supporting their use as temporary implant materials.
• Brittleness and limited size remain challenges for commercialization.

Conclusions:

• Mg-Zn-Ca MGs are highly suitable for temporary implants due to their properties.
• Further research is needed to address limitations in size and brittleness.
• Optimizing fabrication, composition, structure, and reinforcement will enhance their clinical application.