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  3. Biodegradable Mg-zn-ca-based Metallic Glasses.
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  3. Biodegradable Mg-zn-ca-based Metallic Glasses.

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Biodegradable Mg-Zn-Ca-Based Metallic Glasses.

Chao Jin1,2, Zhiyuan Liu3,4, Wei Yu5,6

  • 1Key Laboratory for New Type of Functional Materials in Hebei Province, School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300401, China.

Materials (Basel, Switzerland)
|March 25, 2022

View abstract on PubMed

Summary
This summary is machine-generated.

Biodegradable magnesium-zinc-calcium metallic glasses offer enhanced strength and biocompatibility for temporary implants. Overcoming brittleness and size limitations is key for their commercialization.

Keywords:
Mg–Zn–Cabiodegradableimplantmetallic glass

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Area of Science:

  • Biomaterials Science
  • Materials Engineering
  • Biomedical Engineering

Background:

  • Biodegradable Mg-Zn-Ca-based metallic glasses (MGs) exhibit superior strength and corrosion resistance over crystalline Mg.
  • These MGs demonstrate excellent biocompatibility in vivo and in vitro, making them promising for temporary implants.

Purpose of the Study:

  • To review the microstructure and mechanical properties of Mg-Zn-Ca-based MGs.
  • To provide a comprehensive understanding of the biocorrosion and biocompatibility of these MGs.
  • To propose future directions for fabrication, composition, structure, and reinforcement.

Main Methods:

  • Literature review of Mg-Zn-Ca-based metallic glasses.
  • Analysis of microstructure and mechanical property data.
  • Synthesis of information on biocorrosion and biocompatibility studies.

    • Main Results:

    • Mg-Zn-Ca MGs show enhanced mechanical properties and corrosion resistance compared to crystalline Mg.
    • Excellent biocompatibility is confirmed, supporting their use as temporary implant materials.
    • Brittleness and limited size remain challenges for commercialization.

    Conclusions:

    • Mg-Zn-Ca MGs are highly suitable for temporary implants due to their properties.
    • Further research is needed to address limitations in size and brittleness.
    • Optimizing fabrication, composition, structure, and reinforcement will enhance their clinical application.