MANAGEMENT OUTCOME OF PREMATURE RUPTURE OF MEMBRANES IN A TERTIARY HEALTH FACILITY IN SOUTH WESTERN NIGERIA

Area of Science:

• Obstetrics and Gynecology
• Perinatal Medicine
• Public Health

Background:

• Pre-labour Rupture of Membranes (PROM) is a significant risk factor for maternal morbidity and mortality.
• Understanding the incidence and outcomes of PROM is crucial for improving maternal and neonatal care.

Purpose of the Study:

• To determine the incidence and management outcomes of PROM at Ladoke Akintola University of Technology Teaching Hospital (LTH), Ogbomoso, Nigeria.
• To analyze the association between gestational age at PROM and various fetal outcomes.

Main Methods:

• A retrospective study analyzed 61 PROM cases managed at LTH over three years.
• Data collected included socio-demographics, obstetrics characteristics, management, and outcomes.
• Statistical analysis used SPSS version 20 with significance set at p<0.05.

Main Results:

• The incidence of PROM was 4.1%, with a perinatal mortality rate of 0.18 per 1000 deliveries.
• Term PROM (67%) was more common than preterm PROM (33%).
• Gestational age at PROM significantly correlated with latency period, fetal birth weight, APGAR score, and NICU admission (p<0.05).

Conclusions:

• High incidence of term PROM observed, with conservative/expectant management demonstrating effectiveness.
• Gestational age at PROM is a key determinant of latency and critical fetal outcomes.
• Effective management strategies should consider gestational age to optimize perinatal outcomes.