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PUERPERAL SEPSIS AT UNIVERSITY COLLEGE HOSPITAL, IBADAN: A 10-YEAR REVIEW
A S Olutoye1, A D Agboola1, O O Bello2,2
1Department of Obstetrics and Gynecology, University College Hospital, Ibadan, Nigeria.
Annals of Ibadan Postgraduate Medicine
|April 3, 2023
Summary
Puerperal sepsis, a major cause of maternal death, had a low prevalence but high fatality rate in Nigeria. Treatment involved antibiotics and surgery, with Cephalosporin and Quinolones showing sensitivity. Prevention is crucial.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Public Health
Background:
- Puerperal sepsis is a significant contributor to maternal morbidity and mortality globally, particularly in developing nations.
- This study addresses the critical need to understand the clinical aspects of puerperal sepsis.
Purpose of the Study:
- To investigate the complications, treatment strategies, and management outcomes of puerperal sepsis.
- To identify prevalent pathogens and their antibiotic sensitivities.
Main Methods:
- A 10-year retrospective review of medical records from University College Hospital, Ibadan, Nigeria.
- Analysis of socio-demographic, obstetric, clinical, treatment, and outcome data.
Main Results:
- Prevalence of puerperal sepsis was 0.83%, with a mean age of 29 years; primiparous women were most affected.
- Klebsiella spp. was the most common isolate, sensitive to third-generation Cephalosporins and Quinolones. Anemia was the most frequent complication.
- Case fatality rate was 16.5%, with intravenous antibiotics used for all cases and laparotomy for abdominopelvic collections.
Conclusions:
- Despite low prevalence, puerperal sepsis presents a high case fatality rate.
- Third-generation Cephalosporins and Quinolones are recommended for treatment. Emphasis on prevention of maternal sepsis is paramount.
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