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Oral immune-mediated disorders with malignant potential/association: An overview.

Shankargouda Patil1, Pradeep Kumar Yadalam2, Jagadish Hosmani3

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Oral immune-mediated disorders arise from abnormal immune responses. Some conditions, like oral lichen planus, carry malignant potential, increasing health risks.

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Area of Science:

  • Oral Medicine
  • Immunology
  • Oncology

Background:

  • Oral immune-mediated disorders stem from dysregulated immune responses.
  • These conditions can range from benign to those with malignant potential or association.

Purpose of the Study:

  • To provide an overview of select oral immune-mediated disorders.
  • To highlight their association with or potential for malignancy.

Main Methods:

  • Literature review and synthesis of existing research.
  • Focus on specific oral diseases including oral lichen planus, Sjogren's syndrome, and others.

Main Results:

  • Identified several oral immune-mediated diseases with varying degrees of malignant association.
  • Highlighted the increased morbidity and mortality linked to these conditions.

Conclusions:

  • Understanding these disorders is crucial for managing associated malignancy risks.
  • Early recognition and management can mitigate severe health outcomes.