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Metastatic melanoma to the small bowel causing intussusception: A case report
Hussein Kharroubi1, Bassam Osman2, Rasha T Kakati2
1Faculty of Medicine, American University of Beirut, Bliss Street, Beirut, PO Box 11-0236, Lebanon.
International Journal of Surgery Case Reports
|March 26, 2022
Summary
Metastatic melanoma can cause recurrent adult intussusception, even after immunotherapy. Surgical intervention may be palliative for this rare gastrointestinal complication of melanoma.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Pathology
Background:
- Melanoma frequently metastasizes to the gastrointestinal (GI) tract.
- Metastatic melanoma causing intussusception is rare, with variable presentations complicating diagnosis.
Purpose of the Study:
- To present a case of recurrent enteric intussusception caused by metastatic melanoma.
- To discuss diagnostic modalities and surgical management strategies for this rare condition.
Main Methods:
- Case report of a 48-year-old woman with metastatic melanoma.
- Review of diagnostic laparoscopy, lesion reduction, and resection.
- Discussion of treatment failure despite dual immunotherapy and chemotherapy.
Main Results:
- The patient experienced recurrent intussusception due to a melanoma lesion despite immunotherapy.
- Diagnostic laparoscopy followed by resection was an effective palliative procedure.
Conclusions:
- Dual immunotherapy after chemotherapy may be insufficient for controlling metastatic melanoma.
- Optimal surgical and oncological management for GI melanoma metastasis requires further study.
