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Avoid Postoperative Pain To Prevent Its Chronification: A Narrative Review.

Antonio Montero Matamala1, Magdi Hanna2, Serge Perrot3

  • 1Department of Surgery, University of Lleida, Lleida, ESP.

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|March 28, 2022
PubMed
Summary

Effective management of acute postoperative pain is crucial to prevent chronic pain. Prompt treatment with multimodal analgesia, such as dexketoprofen/tramadol, offers a safe and effective solution, improving patient outcomes.

Keywords:
acute paindexketoprofendrugs fixed dose combination (fdc)multimodal analgesiapain chronificationtramadol

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Area of Science:

  • Anesthesiology
  • Pain Management
  • Pharmacology

Background:

  • Acute postoperative pain is a common surgical outcome that can transition to chronic pain.
  • Chronic postoperative pain significantly impacts quality of life, leading to mood and sleep disturbances.
  • Early and adequate treatment of acute pain can mitigate the risk of developing chronic pain.

Purpose of the Study:

  • To review current strategies for managing acute postoperative pain.
  • To highlight the benefits of a multimodal approach in pain management.
  • To discuss the efficacy and safety of dexketoprofen/tramadol as a fixed-dose combination for postoperative pain.

Main Methods:

  • Literature review of agents used for postoperative pain management.
  • Discussion of patient-specific factors influencing pain intensity and duration.
  • Emphasis on multimodal analgesia principles and fixed-dose combination products.

Main Results:

  • Multimodal analgesia, combining agents with complementary mechanisms, is recommended.
  • This approach can reduce adverse events and opioid consumption.
  • Dexketoprofen/tramadol (DEX-TRA) is identified as a safe and effective fixed-dose combination.

Conclusions:

  • Prompt and adequate treatment of acute postoperative pain is essential to prevent chronification.
  • A multimodal strategy, potentially including DEX-TRA, is effective for managing postoperative pain.
  • Considering patient factors alongside surgical details optimizes pain management outcomes.