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Long-term supplementation with an undenatured type-II collagen (UC-II®) formulation in dogs with degenerative joint
Miguel Ángel Cabezas1, Javier Benito2, Álvaro Ortega3
1Department of Medicine and Surgery, Faculty of Veterinary Medicine, Puerta de Hierro, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Background:
Undenatured type-II collagen (UC-II®) has demonstrated its benefits in degenerative joint disease (DJD) management.
Aim:
Exploratory clinical study to investigate the beneficial effects of FLEXADIN® Advanced in dogs.
Methods:
Multicentre clinical prospective study, 110 client-owned dogs with a clinical diagnosis of DJD. Dogs received FLEXADIN® Advanced during 6 months. Pain, general condition, appetite, mobility, and lameness were assessed monthly by veterinarians and owners for 6 months. Compliance was assessed at 3 and 6 months. Statistical analysis was performed with non-parametric tests (significance, p < 0.05).
Results:
Parameters assessed were significantly lower comparing inclusion with all subsequent months (p < 0.0001). Compliance at 3 months showed a good score but was significantly lower (p < 0.0001) at 6 months.
Conclusion:
FLEXADIN® Advanced, containing UC-II®, can be considered as a good complementary feed to provide joint support in dogs with mild to moderate DJD.
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