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Properties of Organometallic Compounds01:23

Properties of Organometallic Compounds

1.2K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
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Molecules with Multiple Chiral Centers02:25

Molecules with Multiple Chiral Centers

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Molecules that possess multiple chiral centers can afford a large number of stereoisomers. For instance, while some molecules like 2-butanol have one chiral center, defined as a tetrahedral carbon atom with four different substituents attached, several molecules like butane-2,3-diol have multiple chiral centers. A simple formula to predict the number of stereoisomers possible for a molecule with n chiral centers is 2n. However, there can be a lower number where some of the stereoisomers are...
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Metal-Ligand Bonds02:51

Metal-Ligand Bonds

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The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
21.6K
Chirality02:25

Chirality

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Chirality is a term that describes the lack of mirror symmetry in an object. In other words, chiral objects cannot be superposed on their mirror images. For example, our feet are chiral, as the mirror image of the left foot, the right foot, cannot be superposed on the left foot.
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
26.2K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

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Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
28.1K
Prochirality02:05

Prochirality

4.1K
The concept of prochirality leads to the nomenclature of the individual faces of a molecule and plays a crucial role in the enantioselective reaction. It is a concept where two or more achiral molecules react to produce chiral products. A typical process is the reaction of an achiral ketone to generate a chiral alcohol. Here, the achiral reactant reacts with an achiral reducing agent, sodium borohydride, to generate an equimolar mixture of the chiral enantiomers of the product. For example, an...
4.1K

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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
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Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs

Published on: January 17, 2020

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Chiral Metal-Organic Frameworks.

Wei Gong1, Zhijie Chen1, Jinqiao Dong1

  • 1School of Chemistry and Chemical Engineering, Frontiers Science Center for Transformative Molecules and State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, P.R. China.

Chemical Reviews
|March 28, 2022
PubMed
Summary
This summary is machine-generated.

Chiral metal-organic frameworks (CMOFs) offer tunable porous materials for advanced applications. This review highlights CMOF design, synthesis, and their use in asymmetric catalysis, separation, and sensing.

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Synthesis and Characterization of Functionalized Metal-organic Frameworks
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Area of Science:

  • Materials Science
  • Coordination Chemistry
  • Chirality Chemistry

Background:

  • Metal-organic frameworks (MOFs) are crystalline porous materials with tunable properties, distinct from traditional porous materials.
  • Chiral MOFs (CMOFs) have emerged as specialized materials for applications requiring enantioselectivity.
  • CMOFs integrate principles from chirality, coordination, and material chemistry.

Purpose of the Study:

  • To systematically review recent advancements in chiral metal-organic frameworks (CMOFs).
  • To summarize design strategies, synthetic approaches, and applications of CMOFs.
  • To facilitate the rational design and industrial implementation of multifunctional CMOFs.

Main Methods:

  • Literature review of CMOF research.
  • Analysis of design strategies and synthetic methodologies.
  • Highlighting applications in asymmetric catalysis, enantioselective separation, recognition, and sensing.

Main Results:

  • CMOFs offer unique advantages over traditional porous materials due to their designability and functionality.
  • Significant progress has been made in the synthesis and application of CMOFs.
  • CMOFs have demonstrated success in key areas like asymmetric catalysis and enantioselective separation.

Conclusions:

  • CMOFs represent a rapidly advancing field with broad interdisciplinary relevance.
  • Further research can lead to the development of multifunctional CMOFs for industrial applications.
  • This review provides a comprehensive understanding of CMOF chemistry and future prospects.