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[BCG-therapy as a rare reason for postrenal failure].
Maike Metzen1, Michael Kowar1, Gerold Solleder2
1Klinik für Geriatrie mit Neurologie und Tagesklinik, Johanniter-Krankenhaus Bonn.
Bacillus Calmette-Guérin (BCG) therapy for bladder cancer can rarely cause ureteral stenosis, leading to acute renal failure. Prompt treatment with a double-J catheter restored normal kidney function in this case.
Area of Science:
- Nephrology
- Urology
- Oncology
Background:
- Bladder cancer treatment often involves Bacillus Calmette-Guérin (BCG) immunotherapy.
- Acute renal failure is a potential complication, though postrenal causes are infrequent.
Observation:
- A patient undergoing BCG therapy for bladder cancer developed acute renal failure.
- Cystoscopy confirmed bilateral intramural narrowing of the distal ureters, consistent with BCG-induced ureteral stenosis.
Findings:
- The patient presented with urinary congestion (Level II-III) secondary to bilateral ureteral stenosis.
- Renal function normalized after the placement of a double-J catheter.
Implications:
- BCG-induced ureteral stenosis should be considered in the differential diagnosis of postrenal failure in patients receiving BCG therapy.
- This case highlights the importance of recognizing rare but serious side effects of immunotherapy.
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