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Colorectal Cancer Mortality in Kazakhstan: Spatio-Temporal Epidemiological Assessment.
Dana Mauyenova1,2, Askhat Axarin1,2, Zhansaya Telmanova1,2
1Astana Medical University, Nur-Sultan, Kazakhstan.
Colorectal cancer (CRC) mortality in Kazakhstan shows a stable decreasing trend, with rates falling from 11.2 to 7.7 per 100,000. This study highlights regional variations and the need for targeted anti-cancer measures.
Area of Science:
- Oncoepidemiology
- Public Health
- Cancer Research
Background:
- Colorectal cancer (CRC) poses a significant public health challenge globally.
- Understanding mortality trends is crucial for effective cancer control strategies.
- Kazakhstan has specific demographic and healthcare factors influencing CRC outcomes.
Purpose of the Study:
- To analyze temporal trends in colorectal cancer mortality within Kazakhstan.
- To identify age-specific and regional variations in CRC mortality rates.
- To provide data for optimizing cancer control interventions in the region.
Main Methods:
- Retrospective oncoepidemiological study utilizing descriptive and analytical methods.
- Analysis of mortality data from 2009-2018, sourced from the central registration bureau.
- Calculation of crude, age-specific, and age-standardized mortality rates, considering age-sex differences.
Main Results:
- Overall CRC mortality in Kazakhstan demonstrated a decreasing trend from 11.2 to 7.7 per 100,000 population (T=-3.6%).
- Peak mortality was observed in the 60-84 age group, with increasing trends in younger adults (30-34 years) and decreasing trends in older adults (75-79 years).
- Regional variations in mortality rates were identified, with some areas showing a decrease in deaths.
Conclusions:
- Recent trends indicate a stable decrease in colorectal cancer mortality in Kazakhstan.
- Regional mortality analysis is vital for monitoring and evaluating early detection and treatment effectiveness.
- Findings should inform health authorities in organizing targeted anti-cancer measures.
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