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Updated: Sep 28, 2025
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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
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Thyroid dysfunction on the heart: clinical effects, prognostic impact and management strategies
Giulia Mattesi1, Sara Di Michele2, Donato Mele3
1Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua Medical School, Padua. giulia.mattesi@aopd.veneto.it.
Summary
Thyroid hormones significantly impact heart health, affecting both function and structure. This review explores how thyroid dysfunction, including hypothyroidism and hyperthyroidism, alters cardiovascular pathophysiology and its molecular basis.
Area of Science:
- Cardiovascular Science
- Endocrinology
Background:
- Thyroid hormones play a crucial role in regulating cardiovascular function and structure.
- Both hypothyroidism and hyperthyroidism exhibit significant effects on the cardiovascular system.
Approach:
- This review synthesizes current research on the cardiovascular implications of thyroid dysfunction.
- It examines the direct and indirect effects of thyroid hormones on the cardiovascular system.
- The review delves into the molecular mechanisms underlying these changes.
Key Points:
- Thyroid dysfunction profoundly impacts cardiac pathophysiology.
- Molecular mechanisms link thyroid hormone levels to cardiovascular alterations.
- Understanding these links is vital for managing thyroid-related heart conditions.
Conclusions:
- Thyroid hormone imbalance significantly affects cardiovascular health.
- Further research into molecular mechanisms can lead to improved therapeutic strategies.
- Comprehensive understanding of thyroid hormone's cardiovascular effects is essential.
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