Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-heating-induced blocking in nanopores enables neuromorphic ionic computing.

Nature communications·2026
Same author

Electromechanical thermal coupling model and performance compensation methods for slotted waveguide array antenna.

Scientific reports·2026
Same author

A Microscopic Origin for the Breakdown of the Stokes-Einstein Relation in Ion Transport.

The journal of physical chemistry letters·2026
Same author

Multi-Objective Optimization for Through-Silicon via Structure Considering Thermomechanical Reliability and Electrical Performance.

Micromachines·2026
Same author

An explainable ensemble learning-based auxiliary diagnosis system for cerebral small vessel disease.

Scientific reports·2026
Same author

Microscopic mechanisms of helical protein unfolding under thermal and confinement effects.

Colloids and surfaces. B, Biointerfaces·2026

Related Experiment Video

Updated: Sep 28, 2025

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

13.7K

Fabrication of solid-state nanopores.

Kabin Lin1, Chen Chen2, Congsi Wang1

  • 1Key Laboratory of Electronic Equipment Structure Design, Ministry of Education, School of Mechano-Electronic Engineering, Xidian University, Xi'an 710071, People's Republic of China.

Nanotechnology
|March 29, 2022
PubMed
Summary

Solid-state nanopores offer advanced single-molecule sensing for DNA, RNA, and proteins, driving precision medicine. This review details fabrication advances, material choices, and drilling techniques for these vital biosensing tools.

Keywords:
fabrication techniquemembrane materialsolid-state nanopore

More Related Videos

Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.7K
Fabricating Nanogaps by Nanoskiving
07:36

Fabricating Nanogaps by Nanoskiving

Published on: May 13, 2013

11.2K

Related Experiment Videos

Last Updated: Sep 28, 2025

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores
09:43

Fine-tuning the Size and Minimizing the Noise of Solid-state Nanopores

Published on: October 31, 2013

13.7K
Monitoring Protein Adsorption with Solid-state Nanopores
08:51

Monitoring Protein Adsorption with Solid-state Nanopores

Published on: December 2, 2011

13.7K
Fabricating Nanogaps by Nanoskiving
07:36

Fabricating Nanogaps by Nanoskiving

Published on: May 13, 2013

11.2K

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Materials Science

Background:

  • Nanopores are crucial single-molecule sensing tools for detecting biomolecules like DNA, RNA, and proteins.
  • Solid-state nanopores are increasingly important for precision medicine due to their adaptability and semiconductor fabrication compatibility.

Purpose of the Study:

  • To review recent advancements in solid-state nanopore fabrication.
  • To analyze the advantages and disadvantages of various membrane materials and nanopore drilling techniques.

Main Methods:

  • Review of scientific literature on nanopore fabrication and modification.
  • Analysis of different materials and techniques used in solid-state nanopore creation.

Main Results:

  • Solid-state nanopore technology has seen significant progress due to advances in semiconductor fabrication, materials science, and surface chemistry.
  • A variety of materials, processing technologies, and modification methods are now available for nanopore preparation.

Conclusions:

  • Solid-state nanopores represent a rapidly developing field with diverse applications in biosensing and medicine.
  • Understanding the properties of different materials and fabrication techniques is key to optimizing nanopore performance.