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The Longitudinal Evolution of Post-COVID-19 Outcomes Among Hemodialysis Patients in Turkey

Savas Ozturk1, Kenan Turgutalp2, Mustafa Arici3

  • 1Division of Nephrology, Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

Kidney International Reports
|March 30, 2022
PubMed

Insights

Hemodialysis patients who recovered from COVID-19 experienced higher mortality and more complications like respiratory issues and AV fistula thrombosis compared to those without COVID-19.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Hemodialysis (HD) patients face elevated short-term risks from COVID-19.
  • Limited data exists on post-COVID-19 complications and survival in this vulnerable population.

Purpose of the Study:

  • To investigate the post-COVID-19 complications and survival rates in maintenance HD patients.
  • To compare outcomes between HD patients with and without a history of COVID-19.

Main Methods:

  • A national, multicenter observational study included 1223 adult maintenance HD patients.
  • Patients were divided into a COVID-19 recovery group (635) and a control non-COVID-19 group (588).
  • Outcomes were assessed during the first 90 days post-COVID-19 recovery and compared to controls.

Main Results:

  • The COVID-19 group showed higher 28-day (3.0% vs 0%) and 28-90 day (2.4% vs 0.7%) mortality.
  • Increased rates of respiratory symptoms, rehospitalization, home oxygen need, lower respiratory tract infections, and AV fistula thrombosis were observed in the COVID-19 group.
  • Independent predictors for 90-day mortality included age, COVID-19 group status, and vascular access type (tunneled catheter/AV fistula).

Conclusions:

  • Maintenance HD patients with prior COVID-19 face significantly increased risks of rehospitalization, respiratory issues, vascular access complications, and mortality.
  • These findings highlight the prolonged impact of COVID-19 on hemodialysis patients, necessitating targeted monitoring and care.
Abstract

Keywords:
COVID-19hemodialysisnationwide studyoutcome

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