Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

DNA Microarrays

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hemagglutinin double-mutation enhances binding of human-infecting avian influenza virus clade 2.3.4.4b H5Ny to human and SLe<sup>X</sup> receptors.

EMBO reports·2026

Same author

A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET.

bioRxiv : the preprint server for biology·2026

Same author

The Common Fund Data Ecosystem (CFDE).

bioRxiv : the preprint server for biology·2026

Same author

Resources for screening the literature for glycan-related terms using PubAnnotation in GlyCosmos.

Glycobiology·2026

Same author

Establishing the Asia & Pacific Bioinformatics Joint Congress: a historic milestone in regional bioinformatics collaboration.

Briefings in bioinformatics·2025

Same author

Meeting report on the 1st GlyCosmos Symposium & Jamboree-community-driven expansion of glycan-binding molecules resources.

Glycobiology·2025

Search research articles

Related Experiment Video

Updated: Sep 28, 2025

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Published on: February 5, 2018

CarbArrayART: a new software tool for carbohydrate microarray data storage, processing, presentation, and reporting.

Yukie Akune¹, Sena Arpinar², Lisete M Silva^1,3

¹Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College, Du Cane Road, London W12 0NN, United Kingdom.

|March 30, 2022

Summary

This summary is machine-generated.

A new software, Carbohydrate microArray Analysis and Reporting Tool (CarbArrayART), manages glycan microarray data. It aids in storing, analyzing, and exporting data, improving reproducibility in glycobiology research.

Keywords:

glycan microarray data management glycan microarray data presentation glycan microarray data storage glycan microarray software glycoinformatics

More Related Videos

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Published on: February 14, 2019

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

Related Experiment Videos

Last Updated: Sep 28, 2025

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Published on: February 5, 2018

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Printed Glycan Array: A Sensitive Technique for the Analysis of the Repertoire of Circulating Anti-carbohydrate Antibodies in Small Animals

Published on: February 14, 2019

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries

Published on: August 12, 2019

Area of Science:

Glycobiology
Bioinformatics
Computational Biology

Background:

Glycan microarrays are crucial for identifying glycan ligands in biological systems.
Effective data management is essential for analyzing complex glycan microarray experiments.

Purpose of the Study:

To develop a distributable software application for glycan microarray data management.
To enhance the analysis, storage, and reporting of glycan microarray data.

Main Methods:

Development of Carbohydrate microArray Analysis and Reporting Tool (CarbArrayART) software.
Integration of data storage, visualization (charts, tables, heatmaps), and filtering functionalities.
Implementation of data export options compliant with MIRAGE guidelines.

Main Results:

CarbArrayART enables storage of quantified array data with comprehensive metadata.
The software provides tools for data presentation and analysis based on fluorescence intensity.
Export functionality ensures data compatibility with reporting standards like MIRAGE.

Conclusions:

CarbArrayART facilitates routine management of slide-based glycan microarray experiments.
The software enhances data clarity, supporting the evaluation of reproducibility and validity in glycobiology.
Adherence to MIRAGE guidelines ensures standardized and reliable glycomics data reporting.