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Viability Assays for Cells in Culture
Published on: January 20, 2014
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A dual-response NIR probe reveals positive correlation between biothiols and viscosity under cellular stress change
Sha Li1, Fangjun Huo2, Ying Wen1
1Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education, Key Laboratory of Materials for Energy Conversion and Storage of Shanxi Province, Institute of Molecular Science, Shanxi University, Taiyuan 030006, China. yincx@sxu.edu.cn.
Abstract:
A mitochondrial targeted NIR fluorescent probe NIR-NBD was designed and developed for the detection of biothiols and viscosity. Furthermore, a positive correlation between the biothiol level and viscosity under cellular stress change was found for the first time, which provides some important correlation analysis information in the pathophysiological state.

