Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Physiological adaptation to physical conditioning. Old problems revisited.

B Saltin

    Acta Medica Scandinavica. Supplementum
    |January 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Sustained sympathetic activity in altitude acclimatizing lowlanders and high-altitude natives.

    Scandinavian journal of medicine & science in sports·2017
    Same author

    Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases.

    Scandinavian journal of medicine & science in sports·2015
    Same author

    The "Saltin-Grimby Physical Activity Level Scale" and its application to health research.

    Scandinavian journal of medicine & science in sports·2015
    Same author

    Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and Caucasians in the arctic winter.

    Scandinavian journal of medicine & science in sports·2015
    Same author

    Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity.

    Scandinavian journal of medicine & science in sports·2015
    Same author

    Central and peripheral hemodynamics in exercising humans: leg vs arm exercise.

    Scandinavian journal of medicine & science in sports·2015
    Same journal

    Giving life, giving death: ethical problems of high-technology medicine.

    Acta medica Scandinavica. Supplementum·1988
    Same journal

    Potential importance of the muscles for the development of insulin resistance in obesity.

    Acta medica Scandinavica. Supplementum·1988
    Same journal

    Potential role of adipose tissue for the development of insulin resistance in obesity.

    Acta medica Scandinavica. Supplementum·1988
    Same journal

    Mechanisms associating body fat distribution to glucose intolerance and diabetes mellitus: window with a view.

    Acta medica Scandinavica. Supplementum·1988
    Same journal

    Physical training and changes in regional adipose tissue distribution.

    Acta medica Scandinavica. Supplementum·1988
    Same journal

    Hormonal abnormalities in obesity.

    Acta medica Scandinavica. Supplementum·1988
    See all related articles

    The heart's pumping capacity limits maximal oxygen uptake during exercise, as muscle capacity exceeds oxygen supply. Physical conditioning improves exercise response through local metabolic adaptations and altered autonomic control, not just oxygen delivery.

    Area of Science:

    • Exercise Physiology
    • Cardiovascular Regulation
    • Skeletal Muscle Metabolism

    Background:

    • Understanding the physiological limits of human exercise performance is crucial.
    • Adaptive responses to exercise involve complex interactions between cardiovascular and muscular systems.
    • Classical problems in exercise physiology include factors limiting maximal oxygen uptake and metabolic adaptations to training.

    Purpose of the Study:

    • To review key adaptive responses to exercise in humans.
    • To propose that cardiac pump capacity limits maximal oxygen uptake.
    • To explore the mechanisms behind reduced heart rate and altered metabolism following physical conditioning.

    Main Methods:

    • Review of existing literature and physiological evidence.

    Related Experiment Videos

  • Analysis of the relationship between cardiac output, oxygen delivery, and skeletal muscle capacity.
  • Examination of autonomic nervous system activity and local regulatory mechanisms in response to exercise.

    • Main Results:

    • Skeletal muscle's oxygen consumption capacity significantly exceeds the heart's delivery capacity.
    • Engaging large muscle masses during intense exercise necessitates vasoconstriction to maintain blood pressure.
    • Physical conditioning leads to decreased submaximal heart rate via altered autonomic control and enhanced stroke volume.
    • Altered metabolic responses post-conditioning, such as increased lipid oxidation, are attributed to local muscle mechanisms.

    Conclusions:

    • Cardiac pump capacity is a primary determinant of maximal oxygen uptake in humans.
    • Physical conditioning induces beneficial adaptations in cardiovascular control and muscle metabolism.
    • Local metabolic responses within exercising muscles play a significant role in modulating systemic cardiovascular regulation during exercise.