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Pompholyx as a side effect of intravenous immunoglobulin (IVIg)

Claire Doyle1, Karen Eustace2

  • 1Dermatology, Beaumont Hospital, Dublin, Ireland doylec32@tcd.ie.

BMJ Case Reports
|March 31, 2022
PubMed

Intravenous immunoglobulin (IVIg) is increasingly used across multiple specialties for the treatment of inflammatory and autoimmune diseases. Cutaneous reactions to IVIg are generally minor. Pompholyx is a common eruption of small vesicles on the palms, soles, and/or lateral aspects of the fingers. It has a multifactorial aetiology but is rarely attributed to being a drug-related side effect. We describe a 43-year-old woman presenting with peripheral sensory neuropathy who developed pompholyx eczema on both palms following treatment with IVIg.

Keywords:
DermatologyDrugs and medicinesSkin

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