Related Experiment Video
Updated: Sep 28, 2025

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
Published on: September 9, 2022
[The efficacy of eculizumab against post-thymectomy exacerbations in thymoma associated myasthenia gravis (MG)]
Eriko Takeuchi1, Yuta Kajiyama1,2, Koshiro Ando3,4
1Department of Neurology, Osaka University Graduate School of Medicine.
Abstract:
We report a 62-year-old woman with thymoma associated myasthenia gravis (MG). She had significant dysphagia and was treated with corticosteroids, intravenous immunoglobulin (IVIG), immunoadsorption plasmapheresis (IAPP), and immunosuppressive drugs, and the extended thymectomy. Her symptoms gradually improved, but 3 weeks after thymectomy, her bulbar symptoms recurred. Although she was treated with repeated IVIG and IAPP, her symptom remained. Finally, after starting eculizumab did her symptoms go into complete remission. This case suggests the efficacy of anti-complement therapy for postoperative exacerbation of MG.
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