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Acute Dacryoadenitis due to Primary Epstein-Barr Virus Infection
Satoshi Hayano1, Naruhiko Nakada1, Masayuki Kashima1
1Department of Internal Medicine, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
Open Forum Infectious Diseases
|March 31, 2022
Summary
Epstein-Barr virus (EBV) infection can cause acute dacryoadenitis, a rare complication affecting the lacrimal glands. This case highlights the importance of considering ocular symptoms in diagnosing primary EBV infections.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Virology
Background:
- Primary Epstein-Barr virus (EBV) infection typically presents with infectious mononucleosis symptoms.
- Ocular manifestations of EBV are uncommon but can occur.
- Acute dacryoadenitis, inflammation of the lacrimal glands, is a rare presentation of EBV.
Observation:
- A 28-year-old male presented with fever and bilateral upper eyelid swelling.
- No other upper airway symptoms were reported.
- Physical examination and CT scans confirmed lacrimal gland swelling.
Findings:
- Laboratory tests showed lymphocytosis with atypical lymphocytes and abnormal liver function.
- Serological tests confirmed Epstein-Barr virus infection.
- The patient was diagnosed with acute dacryoadenitis secondary to EBV.
Implications:
- Acute dacryoadenitis should be considered in the differential diagnosis of EBV-related ocular symptoms.
- This case underscores the importance of recognizing rare complications of primary EBV infection.
- Early diagnosis and management of EBV-induced dacryoadenitis are crucial.

