Related Experiment Video
Updated: Sep 28, 2025
08:36
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
Published on: April 19, 2024
747
Seroepidemiological Studies on Japanese Encephalitis: A Systematic Review
Nur Suhada Ramli1, Norayuni Mohd Ismail1, Na'eemah Zaini1
1Department of Community Health, Faculty of Medicine, National University of Malaysia, Cheras, Kuala Lumpur, Malaysia.
Oman Medical Journal
|March 31, 2022
Summary
Japanese encephalitis virus (JEV) seroprevalence increases with age, highlighting the need for vaccination. Continuous monitoring of JEV immunity and susceptibility is crucial for public health strategies.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Japanese encephalitis (JE) is a significant mosquito-borne illness in the Western Pacific, causing 20%-30% mortality.
- Fluctuating JE virus (JEV) seroprevalence necessitates ongoing research for effective prevention and control.
- Understanding age-specific JEV seroprevalence aids in identifying population immunity and susceptibility for vaccination planning.
Purpose of the Study:
- To determine the trend of age-specific Japanese encephalitis virus (JEV) seroprevalence.
- To map JEV seroprevalence across different age groups to inform public health interventions.
Main Methods:
- A systematic review of JEV seroprevalence studies published between 2010 and 2019 was conducted.
- PubMed and Web of Science databases were searched, adhering to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
- Data from eligible studies were extracted and analyzed to identify trends in age-specific seroprevalence.
Main Results:
- Four studies from Taiwan, Sri Lanka, South Korea, and India met the inclusion criteria.
- An increasing trend of JEV seropositivity was observed with advancing age across all included countries.
- South Korea exhibited the highest seroprevalence (97.8%-98.3%), likely due to early and mandatory vaccination, while India had the lowest (12.9%-18.1%).
Conclusions:
- Immunization has significantly reduced reported JE cases.
- The persistence of JEV in nature and zoonotic cycles means infection risk remains.
- Integrating JEV vaccination into national immunization programs, particularly for young children, is essential for continued control.
More Related Videos
12:20Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
21.5K
06:22Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children
Published on: February 10, 2023
1.1K
Related Concept Videos
01:29Bias in Epidemiological Studies
742
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
742
01:25Statistical Methods for Analyzing Epidemiological Data
581
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
581
01:20Study Designs in Epidemiology
461
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
461
01:27Confounding in Epidemiological Studies
291
Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
291
01:26Introduction to Epidemiology
1.1K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.1K
01:26Principles of Disease Surveillance
202
Disease surveillance is the systematic collection, analysis, and interpretation of health data essential to the planning, implementation, and evaluation of public health practice. This process integrates data dissemination to entities responsible for preventing and controlling disease, injury, and disability. Surveillance systems provide crucial information for action, helping public health authorities make informed decisions to manage and prevent outbreaks, ensure public safety, optimize...
202