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Mind the "Vaccine Fatigue".

Zhaohui Su1, Ali Cheshmehzangi2,3, Dean McDonnell4

  • 1Center on Smart and Connected Health Technologies, Mays Cancer Center, School of Nursing, UT Health San Antonio, San Antonio, TX, United States.

Frontiers in Immunology
|April 1, 2022
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Summary
This summary is machine-generated.

Vaccine fatigue, driven by perceived burden, stems from immunization demands and mistrust. Effective, empathetic communication is key to overcoming public inaction towards vaccines.

Keywords:
COVID-19public healthvaccinationvaccine communicationsvaccine fatigue

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Area of Science:

  • Public Health
  • Behavioral Science
  • Epidemiology

Background:

  • The COVID-19 pandemic and Omicron variant have intensified vaccine discussions.
  • Vaccine fatigue, a growing concern, lacks systematic research into its contributing factors.
  • Understanding vaccine fatigue is crucial for effective public health strategies.

Purpose of the Study:

  • To systematically investigate the antecedents of vaccine fatigue.
  • To identify factors contributing to public inertia or inaction regarding vaccination.

Main Methods:

  • A narrative literature review was conducted across PubMed, Scopus, and PsycINFO.
  • The review focused on scholarly articles published in English up to December 6, 2021.
  • 37 relevant articles were analyzed to identify key themes and factors.

Main Results:

  • Vaccine fatigue is discussed across various infectious diseases and populations, including the general public, parents, and healthcare professionals.
  • Identified antecedents include frequent immunization demands, vaccine side effects, misconceptions about disease severity, and distrust in government and media.
  • Factors range from inherent vaccine science limitations to communication-related issues.

Conclusions:

  • Vaccine fatigue is defined as inertia or inaction due to perceived burden and burnout.
  • While some causes are linked to vaccine science, many are preventable.
  • Empathetic and effective vaccine communication strategies can mitigate vaccine fatigue across society.