Electrophysiologic aspects of amblyopia

This paper presents a sampling of the psychophysical and electrophysiologic examinations which have been applied to determine the location of the visual processing defect in functional amblyopia. Areal summation and lateral inhibition are discussed along with methods for determining their extent at different locations in the visual system. Using psychophysical and visual-evoked response data from a series of these tests in humans, a case is made that the outer retina is the locus of a major defect leading to the loss of visual resolution in functional amblyopia.