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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

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Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

14.5K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

6.3K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Updated: Sep 28, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Equity in Genomic Medicine.

Chanita Hughes Halbert1,2

  • 1Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA;

Annual Review of Genomics and Human Genetics
|April 1, 2022
PubMed
Summary
This summary is machine-generated.

Genomic medicine advances precision healthcare, but unequal access risks widening health disparities. Prioritizing equitable access and research in genomic medicine is crucial for all populations.

Keywords:
equitygenomic medicineminority healthtranslational research

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Area of Science:

  • Genomic Medicine
  • Precision Health
  • Health Equity

Background:

  • The Human Genome Project has spurred advances in understanding genetic disease risk and treatment response.
  • Precision medicine approaches are expected to improve early detection, prevention, and treatment, potentially enhancing healthcare equity.
  • Unequal access to genomic medicine research and services can worsen existing health disparities.

Purpose of the Study:

  • To identify challenges to equity in genomic medicine.
  • To explore opportunities and future directions for addressing these challenges.

Main Methods:

  • Literature review and synthesis of current challenges and opportunities in genomic medicine.
  • Analysis of access barriers and potential solutions for disparity populations.

Main Results:

  • Reduced access to genomic medicine research, clinical services, and public health interventions can exacerbate health disparities.
  • Targeted efforts are needed to improve access for underserved populations.

Conclusions:

  • Enhancing access to genomic medicine research, clinical services, and public health interventions is essential.
  • Prioritizing research on the clinical utility of precision medicine in disparity populations is critical for achieving health equity.