Biosensors as diagnostic tools in clinical applications
C Lino1, S Barrias1, R Chaves2
1University of Trás-os-Montes e Alto Douro, School of Life Science and Environment, Department of Genetics and Biotechnology, Blocos Laboratoriais bdg, 5000-901 Vila Real, Portugal; BioISI - Biosystems & Integrative Sciences Institute, University of Lisboa, Faculty of Sciences, Campo Grande, C8 bdg, 1749-016 Lisboa, Portugal.
Biochimica Et Biophysica Acta. Reviews on Cancer
|April 3, 2022
Summary
Biosensors and biomarkers are revolutionizing medical diagnostics. This review explores recent advancements in biosensing technology and its clinical applications for earlier disease detection and improved patient outcomes.
Area of Science:
- Biotechnology and Biomedical Engineering
- Molecular Diagnostics
- Medical Technology Innovation
Background:
- The medical field prioritizes technological advancements, particularly in biosensors, attracting significant scientific and financial investment.
- Genomic advances have identified specific disease biomarkers, crucial for clinical diagnosis, health management, and treatment.
- Biosensors, despite exponential growth, have had limited clinical applications relative to their potential.
Purpose of the Study:
- To review recent developments in biosensor technology.
- To explore the clinical applications of advanced biosensing devices.
- To highlight the potential of biosensors and biomarkers in revolutionizing healthcare.
Main Methods:
- Review of recent scientific literature on biosensor technology.
- Analysis of emerging biosensing devices and their components (bioreceptors).
- Examination of clinical applications across various disease types.
Main Results:
- Biosensors offer fast, cost-effective, reliable, and highly sensitive diagnostic capabilities.
- A wide range of bioreceptors (nucleic acids, antibodies, enzymes, cells) enable diverse disease detection.
- Early clinical diagnosis through biosensors can significantly improve patient survival and prognosis.
Conclusions:
- The integration of biomarkers with biosensor technology holds immense potential for transforming healthcare.
- Biosensing platforms provide accessible tools for early diagnosis of infections, cancer, and metabolic disorders.
- Continued innovation in biosensors promises earlier and more effective disease management.
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