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Updated: Sep 28, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Acute disseminated encephalitis (ADEM) as the first presentation of COVID-19; a case report
Sara Esmaeili1,2,3,4, Mohammad Hossein Abbasi1,4, Mohammad Taghi Joghataei2,3
1Firoozgar Clinical Research and Development Center FCRDC, Iran University of Medical Sciences IUMS, Tehran, Iran.
Introduction:
and importance: Neurological ailments are reported during and after SARS-COV-2 infection.
Case Presentation:
We report a 67-year-old Iranian man with COVID-19 infection and Acute Disseminated Encephalomyelitis (ADEM) whose neurological symptoms appeared before clinical and radiological pulmonary manifestations.
Clinical Discussion:
COVID-19 can cause neurological complication without entering the CNS via para infectious inflammatory mechanisms.
Conclusions:
This report shows that ADEM might be among primary presentations of COVID-19.

