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Ventricular arrhythmia: management strategy.

R F Malacoff

    The Medical Clinics of North America
    |November 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Managing ventricular arrhythmias is challenging. High-risk patients benefit from invasive and noninvasive strategies, including antiarrhythmic drugs, surgery, and implantable defibrillators.

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    Area of Science:

    • Cardiology
    • Electrophysiology
    • Internal Medicine

    Background:

    • Ventricular arrhythmias pose significant therapeutic challenges.
    • Sudden cardiac death (SCD) remains a critical concern in cardiovascular medicine.
    • Identifying and managing high-risk patient subgroups is essential.

    Purpose of the Study:

    • To review current and experimental therapeutic strategies for ventricular arrhythmias.
    • To highlight management approaches for patients at high risk of SCD.
    • To discuss the role of pharmacologic, surgical, and device-based interventions.

    Main Methods:

    • Review of traditional and experimental antiarrhythmic agents.
    • Discussion of invasive (e.g., map-guided surgical excision) and noninvasive techniques.

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  • Evaluation of the role of automatic implantable defibrillators (AIDs).

    • Main Results:

    • Both invasive and noninvasive methods show success in managing high-risk patients.
    • High-risk groups include resuscitated SCD survivors, patients with ventricular ectopy and left ventricular dysfunction, and post-myocardial infarction patients.
    • Combination therapy may be more effective than monotherapy for some patients.

    Conclusions:

    • Pharmacologic therapy, including combination approaches, is a cornerstone of management.
    • Surgical excision guided by electroanatomic mapping offers an alternative when medical therapy fails.
    • Automatic implantable defibrillators provide a promising option for refractory cases.