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Complete Genome Sequence of Stenotrophomonas maltophilia Podophage Paxi

Eunhye Jeon1, Alexis Hudson1, Andrew Talcott1

  • 1Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA.

Microbiology Resource Announcements
|April 4, 2022
PubMed

Insights

The genome of Stenotrophomonas maltophilia podophage Paxi was sequenced. This N4-like phage is closely related to another S. maltophilia phage, Pokken.

Area of Science:

  • Microbiology
  • Genomics
  • Virology

Background:

  • Stenotrophomonas maltophilia is a multidrug-resistant pathogen causing severe infections in immunocompromised individuals.
  • Bacteriophages are viruses that infect bacteria and are potential therapeutic agents.

Purpose of the Study:

  • To present the complete genome sequence of Stenotrophomonas maltophilia podophage Paxi.
  • To characterize Paxi's genomic relationship with other S. maltophilia phages.

Main Methods:

  • Whole-genome sequencing of S. maltophilia podophage Paxi.
  • Bioinformatic analysis for genome assembly and comparison.

Main Results:

  • The complete genome of S. maltophilia podophage Paxi was assembled, measuring 74,962 bp.
  • Paxi was identified as an N4-like phage.
  • Paxi shares 85.3% nucleotide similarity with S. maltophilia podophage Pokken.

Conclusions:

  • The genomic data of Paxi provides insights into S. maltophilia phage diversity.
  • Understanding phage genomes is crucial for developing phage-based therapies against resistant bacteria.

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