Related Experiment Video
Updated: Sep 28, 2025
04:53
Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
954
Risk Factors for Length of Hospital Stay in Acute Exacerbation Chronic Obstructive Pulmonary Disease: A Multicenter
Hong Wang1, Tao Yang2, Xiaodan Yu3
1Respiratory Medicine, First People's Hospital of Suining City, Suining, 629000, Sichuan, People's Republic of China.
International Journal of General Medicine
|April 5, 2022
Summary
Identifying predictors of prolonged hospital stay in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is crucial. Hypertension, chronic cor pulmonale, and inflammatory markers like NLR and ESR independently predict longer AECOPD hospital stays.
Area of Science:
- Pulmonology
- Internal Medicine
- Critical Care
Background:
- Prolonged length of hospital stay (LHS) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) correlates with disease severity and adverse outcomes.
- Early identification of patients at risk for extended hospital stays can mitigate risks and reduce healthcare costs.
Purpose of the Study:
- To identify independent predictors of prolonged LHS in patients diagnosed with AECOPD.
- To inform early risk stratification and management strategies for AECOPD patients.
Main Methods:
- A multicenter, cross-sectional study involving 598 AECOPD patients across two tertiary hospitals.
- Data collected included demographics, comorbidities, symptoms, and laboratory findings.
- Ordinal logistic regression analysis was employed to determine independent risk factors for prolonged LHS.
Main Results:
- Hypertension, chronic cor pulmonale (CCP), elevated neutrophil-lymphocyte ratio (NLR), and high erythrocyte sedimentation rate (ESR) were identified as independent predictors of prolonged LHS.
- Significant differences in 12 variables were noted in univariate analysis.
- White blood cell count and neutrophil percentage were excluded due to collinearity.
Conclusions:
- Inflammatory status, hypertension, and CCP are independently associated with LHS in AECOPD patients.
- Prompt antibiotic and anti-inflammatory treatment is vital for reducing hospital stay duration.
- Patients with hypertension and/or CCP require advanced management strategies upon admission due to their association with worse outcomes.
Keywords:
acute exacerbation of chronic obstructive pulmonary diseasechronic cor pulmonaleerythrocyte sedimentation ratehypertensionlength of hospital stayneutrophil–lymphocyte ratioMore Related Videos
Related Concept Videos
01:22Chronic Obstructive Pulmonary Disease
1.5K
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
1.5K
01:27Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.6K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.6K
01:20Chronic Obstructive Pulmonary Disease-I: Introduction
3.0K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
3.0K
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
3.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
3.2K
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
3.0K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.0K
01:20COPD: Pathogenesis and Clinical Features
648
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
648