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SIMPA: an open-source toolkit for simulation and image processing for photonics and acoustics.

Janek Gröhl1, Kris K Dreher1,2, Melanie Schellenberg1,3,4

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|April 5, 2022
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Summary

The Simulation and Image Processing for Photonics and Acoustics (SIMPA) toolkit offers open-source tools for simulating optical and acoustic imaging. This facilitates realistic tissue modeling and data-driven approaches in biomedical imaging research.

Keywords:
acoustic imagingopen-sourceoptical imagingphotoacousticssimulation

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Area of Science:

  • Biomedical Imaging
  • Computational Optics
  • Acoustic Physics

Background:

  • Noninvasive optical and acoustic imaging visualize tissue but face quantification challenges due to inverse problems.
  • Data-driven methods require high-quality simulations, yet realistic tissue optical and acoustic properties are often unknown.

Purpose of the Study:

  • Introduce the open-source Simulation and Image Processing for Photonics and Acoustics (SIMPA) Python toolkit.
  • Provide a modular and extensible platform for simulating optical and acoustic imaging modalities.

Main Methods:

  • SIMPA integrates computational forward models, data processing algorithms, and digital device twins into a unified pipeline.
  • The toolkit features modular design for seamless exchange of implementations and includes libraries for biological structures and material properties.
  • Realistic tissue models are generated using customizable simulation pipelines.

Main Results:

  • Demonstrated SIMPA's capabilities using photoacoustic imaging examples.
  • Showcased the diversity of customizable tissue models and simulation pipelines.
  • Highlighted the high degree of realism achievable in simulations.

Conclusions:

  • SIMPA is an open-source toolkit facilitating the simulation of optical and acoustic imaging.
  • The toolkit supports the development and validation of data-driven approaches in biomedical imaging.
  • Available code enables reproduction of simulation examples and further research.