Related Experiment Video
Updated: Sep 28, 2025
11:48
Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
Published on: April 4, 2019
16.2K
Persistent Rhinovirus Infection in a Child With Leukemia
Duygu Özbek Siddiqui1, Tuğba Bedir Demirdağ2, Sirma Karamercan3
1Departments of Pediatrics.
Journal of Pediatric Hematology/Oncology
|April 5, 2022
Summary
Human Rhinovirus (HRV) can cause chronic infections in immunocompromised individuals. This case study highlights a persistent HRV infection in a leukemia patient post-stem cell transplant, underscoring the need for further research.
Area of Science:
- Virology
- Immunology
- Hematology
Background:
- Human Rhinovirus (HRV) is a common cause of acute respiratory infections in children.
- HRV infections can persist in immunocompromised patients, but duration and severity are often unclear.
- Previous reports documented chronic HRV in lung transplant recipients, hypogammaglobulinemia, and cystic fibrosis patients.
Observation:
- This study details a case of persistent HRV infection in a leukemia patient following a stem cell transplant.
- The patient experienced prolonged viral shedding and clinical symptoms.
Findings:
- The case demonstrates a prolonged HRV infection in an acute leukemia patient post-stem cell transplant.
- This highlights a potential complication of HRV in this specific patient population.
Implications:
- Further research is needed to understand risk factors for persistent HRV infection in acute leukemia patients.
- Prospective and longitudinal studies are warranted to clarify the duration and severity of HRV infections in this demographic.
- This case contributes to understanding HRV pathogenesis in immunocompromised hosts.
More Related Videos
09:01An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
8.0K
09:14An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
Published on: January 26, 2019
11.1K
Related Concept Videos
01:03Rous Sarcoma Virus (RSV) and Cancer
5.5K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.5K
01:30Pneumonia I: Introduction
365
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
365
01:30Pneumonia V: Nursing management and Prevention
2.6K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.6K
01:30Acute Pharyngitis
1.8K
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
1.8K
01:23Chronic Pharyngitis
5.8K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
5.8K
01:51Mechanisms of Retrovirus-induced Cancers
5.3K
Retroviruses are RNA viruses that have been shown to cause cancers in diverse species, including chickens, mice, cats, and monkeys. The RNA genomes of these viruses are first reverse-transcribed into single and then double-stranded DNA (dsDNA) copies. This dsDNA called proviral DNA then integrates into the host genome. Subsequently, the host cell transcribes the proviral DNA in concert with the chromosomal DNA. This leads to the production of viral RNA and proteins that assemble at the host...
5.3K