[Preliminary considerations on blood lipid parameters and blood insulin after oral glucose tolerance test]

The behaviour of total lipids, triglycerides and apolipoproteins A and B has been investigated in 41 subjects whose glucose and insulin levels have been evaluated after oral glucose tolerance test. Some of the patients showed a normal glycemic response, others a reduced glucose tolerance. Patients with a normal glycemic curve and a normal pattern of insulin values after loading had low mean total lipids and triglycerides and elevated Apolipo A values. Furthermore, subjects with altered glycemic curve and normal insulin levels presented high mean total lipids and triglycerides and low Apolipo A values. In conclusion we observed, in agreement with other authors, that a good blood insulin reaction is a favourable factor for the reduction of serum triglyceride levels, probably by activation of lipoproteinlipase, with a slight mean increase of apolipoproteins A.