Fabrication of magnetic covalent organic framework for effective and selective solid-phase extraction of...

Efficient magnetic solid phase extraction using crystalline porous polymers can find important applications in food safety. Herein, the core-shell Fe₃O₄@COFs nanospheres were synthesized by one-pot method and characterized in detail. The porous COF shell with large surface area had fast and selective adsorption for propylparaben via π-π, hydrogen bonding and hydrophobic interactions. The extraction and desorption parameters were evaluated in detail. Under the optimized conditions, the extraction equilibrium was reached only in 5 min, the maximum adsorption capacity for propylparaben was 500 mg g^-1 and the proposed Fe₃O₄@DhaTab-based-MSPE-HPLC-UV method afforded good linearity (4-20000 μg mL^-1) with R² (0.997), low limits of detection (0.55 μg L^-1) and limits of quantification (1.5 μg L^-1). Furthermore, the developed method was applied to determine propylparaben in soft drinks with the recoveries (97.0-98.3%) and relative standard deviations (0.61 to 3.75%). These results revealed the potential of Fe₃O₄@DhaTab as efficient adsorbents for parabens in food samples.