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Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
Published on: April 21, 2012
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An Atypical Presentation of Cutaneous Leishmaniasis
Fatimazahra Chahboun1, Madiha Eljazouly1, Maha Alj1
1Dermatology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.
Cureus
|April 6, 2022
Summary
A rare verrucous form of cutaneous leishmaniasis, a parasitic skin infection, was observed in a type 1 diabetic patient. Treatment with meglumine antimoniate and trichloroacetic acid showed promising results.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Cutaneous leishmaniasis presents with diverse clinical manifestations.
- Unusual presentations are often linked to patient immunity or specific parasite strains.
Observation:
- A 36-year-old male with type 1 diabetes developed a verrucous plaque on his left hand six months post-travel to Morocco.
- The lesion was a non-pruritic, non-painful papulo-nodular verrucous growth with a keratotic surface.
Findings:
- Skin biopsy confirmed leishmaniasis bodies via May-Grünwald Giemsa stain.
- The patient received eight weeks of intralesional meglumine antimoniate and trichloroacetic acid (TCA) 20% applications.
- Significant lesion regression was noted within four months of treatment.
Implications:
- This case highlights a rare verrucous presentation of cutaneous leishmaniasis.
- The interplay of parasite factors and diabetes may influence clinical presentation.
- Combined TCA and meglumine antimonate therapy offers a potential treatment strategy for this form.
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